what’s the mean 与你何干

与你何干： What does it have to do with you?

Regarding the reply, it depends on the thing you are discussing..

<span style="color: #2e3033;”>与你何干means  1. What does it have to do with you.

<span style="color: #2e3033;”>                           2. None of your business.

how to answer it :

1. A little free and easy:The dog bit Lu Dong bin…

2. Don’t suffer a loss: you are not saved!Or, you’re hopeless!

<p class="tgt" style="color: #2e3033;”>3. Interesting: I was wrong, you have no medicine to save.

<p class="tgt" style="color: #2e3033;”>4. Touching: I thought we were friends.

Expressing that you are curious about why s/he (want to) did certain things.

If your feelings aren’t in any way equivocal, you could simply say, 关你屁事。But apparently it’s offensive.